Coexpression of neuronatin splice forms promotes medulloblastoma growth
نویسندگان
چکیده
منابع مشابه
Coexpression of neuronatin splice forms promotes medulloblastoma growth.
Medulloblastoma (MB) is the most common pediatric brain cancer. Several important developmental pathways have been implicated in MB formation, but fewer therapeutic targets have been identified. To locate frequently overexpressed genes, we performed a comprehensive gene expression survey of MB. Our comparison of 20 primary tumors to normal cerebellum identified neuronatin (NNAT) as the most fre...
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Failure of white adipose tissue to appropriately store excess metabolic substrate seems to underpin obesity-associated type 2 diabetes. Encouraging "browning" of white adipose has been suggested as a therapeutic strategy to help dispose of excess stored lipid and ameliorate the resulting insulin resistance. Genetic variation at the DNA locus encoding the novel proteolipid neuronatin has been as...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2008
ISSN: 1523-5866,1522-8517
DOI: 10.1215/15228517-2008-038